What's it like being bipolar?

It has its ups and downs.

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Down Jokes More Down Jokes

How is the elevator business?

Oh, it has its up and downs...

What bands did they hire to play at the Developmental Disability Conference?

System of a Downs My Chemical Imbalance. Youth In Asia

Up Jokes More Up Jokes

How is the retarded basketball player doing?

Well, he has his ups and down's.

How did the hail stone describe it's life?

It really has a lot of ups and downs