What's it like being bipolar?

It has its ups and downs.

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Down Jokes More Down Jokes

What do you call an Asian boy with downs?

Lo Mein. See you all in hell.

How's the elevator business?

It has it's ups and downs.

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How did you prepare for today?

red carpet question with "Cocaine and sit ups." #GoldenGlobes

How is the retarded basketball player doing?

Well, he has his ups and down's.